Tuesday, October 4, 2022

Cranberry Juice And Urinary Tract Infections What Is The Evidence

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Cranberries Can Help Prevent Utis

Cranberry Juice to Treat My Urinary Tract Infection | How to cure a UTI

If you go looking for a study that will tell you, definitively, whether or not cranberries will help prevent a UTI, youll encounter mixed results. One 2012 study involving 1616 women with recurrent UTIs found that cranberry juice was effective in preventing infection, while a smaller 2012 study found no evidence to support this claim.

But the newest guidelines, which were released in 2019, give cranberry the thumbs up. A list of recommendations published in the Journal of Urology, suggests that cranberry can be used as a preventive measure for women with recurrent UTIs, given the rising rates of antibiotic-resistant bacteria that can make finding an effective treatment to knock out a bacterial infection more challenging.

Why? Cranberries contain a substance called proanthocyanidins . These PACs are chemical compounds from a family of compounds called polyphenols. These compounds give fruits like cranberries their deep red color.

It prevents the bacteria from sticking to the lining of the bladder, where they can prosper and lead to an infection, says Kathleen Kobashi, a urologist in Seattle.

A 240 milliliter serving of Ocean Spray cranberry juice contains 36mg of PACs, a sufficient concentration for antibacterial purposes. But Kobashi notes that sweetened cranberry juice can be very high in sugar. One cup of sweetened cranberry juice may contain nearly 30 grams of sugar, which exceeds the recommended daily sugar intake of 25 grams per day for women.

The Facts About Cranberries And Utis

More than 20 national and international studies were examined, including randomized controlled research trials, considered the gold standard for evaluating effectiveness of a treatment. These studies evaluated the role cranberries play in preventing or treating a urinary tract infection among a variety of populations, including children, adults, men, women, pregnant women, and those with certain medical conditions.

As of 2020, the current research shows cranberry products provide very little or no benefit in the prevention or treatment of a UTI when compared to a placebo.

Other Ways To Treat A Uti

Doctors most commonly treat a UTI with a regimen of antibiotics. Sometimes mild UTIs will go away on their own, but theres a risk they could get worse, even leading to medical conditions like bladder infection or kidney infection if left untreated.

No home remedy has proved to be as effective as antibiotics for treating a UTI. So while cranberry juice can be a tool in your arsenal to help prevent UTIs, it shouldnt take the place of seeing a urology expert for treatment when you develop an infection. If youre not a fan of the way antibiotics affect your digestive system, use a regimen of probiotics to counter some of those effects.

How do you get rid of a symptomatic UTI fast? Its impossible to cure an infection instantly, as much as you might want to when youre dealing with that burning, stinging feeling. But with a prescription, most UTIs can be cleared up within a week or two, and youll go back to feeling normal ASAP.

Once your UTI is clear, you can focus on hygiene tips to prevent another UTI. Always urinate after sexual activity , wipe toilet paper from front to back, and change out of wet or sweaty clothes within a few hours. This will lower your risk of recurrent urinary tract infections.

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Also Check: Cranberry Supplements For Urinary Health

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(PDF) Cranberry Juice for the Prevention of Recurrences of Urinary ...

Theres no harm in drinking cranberry juice regularly to ward off UTIs theres just no guarantee itll work. However, do make sure youre drinking 100% cranberry juice and not a cocktail, which is mostly grape juice, apple juice, and sugar.

Cranberry juice does pad your diet with extra calories. Even unsweetened, 100% cranberry juice contains 116 calories per cup. That might not seem like a lot, but if you add it without trimming an equal number of calories elsewhere, it could lead you to gain about a pound every month.

If you opt for cranberry supplements, know that the US Food and Drug Administration doesnt regulate them. That means you cant be sure how much active ingredient each dose contains.

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But Many Of The Antibiotics That Worked In The Past Dont Seem To Work Anymore

Many physicians can tell you that they see patients who are particularly susceptible to urinary tract infections. For a long time, we had inexpensive antibiotics that worked really well for this. But over the last 10-15 years, we have seen a huge jump in bacterial infections of UTI that are resistant to many of these drugs.they produce bacteria that are similarly resistant to the antibioticsUnless we take significant actions to improve efforts to prevent infections and also change how we produce, prescribe and use antibiotics…. the implications will be devastating.

How You Actually Can Help Prevent Utis

Dr.Moore says shes heard all of the myths about how to prevent or treat UTIs drinking lots of water, urinating after sex, avoiding tight-fitting pants andstaying away from hot tubs, bubble baths and tampons. None of these beliefs issupported by scientific data, she says.

Onthe other hand, here are three things that Dr. Moore says women should do tohelp prevent UTIs:

  • Take precautions to prevent UTIs after sex. Frequency of sexual activity is strongly correlated with UTIs, she says, and having multiple partners and a history of sexually transmitted diseases put you at the greatest risk. If youre prone to recurrent UTIs, Dr. Moore advises against using spermicides or barrier contraceptives and will often recommend a single dose of an oral antibiotic be taken before or after sex.
  • Develop good bowel habits. UTIs are caused when bacteria from the rectum strays into the vagina, she says. That most commonly happens when you have constipation or diarrhea, so do what you can to stay regular.
  • Eventhough UTIs happen frequently, you can take steps to lower your risk.

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    New Evidence On How Cranberry Juice Fights Bacteria That Cause Urinary Tract Infections

    Note to journalists: Please report that this research was presented at a meeting of the American Chemical Society

    BOSTON, Aug. 23, 2010 Scientists today reported new scientific evidence on the effectiveness of that old folk remedy cranberry juice for urinary tract infections, at the 240th National Meeting of the American Chemical Society , being held here this week.

    A number of controlled clinical trials these are carefully designed and conducted scientific studies done in humans have concluded that cranberry juice really is effective for preventing urinary tract infections, said Terri Anne Camesano, Ph.D., who led the study. That has important implications, considering the size of the problem and the health care costs involved.

    Mechanistic Studies: Antiadherent Properties

    Cranberry Juice and Kidneys | Your Kidneys Your Health | @qasimbuttmd

    Adherence of uropathogens to uroepithelial cells is the initial step in pathogenesis of UTI . In 1984, Sobota was first to suggest that reported benefits derived from the use of cranberry juice may be related to its ability to inhibit bacterial adherence . Sobota found that cranberry juice cocktail reduced adherence by > 75% in > 60% of 77 clinical isolates of E. coli recovered from patients with UTI. Fifteen of 22 subjects showed significant antiadherence activity in their urine 13 h after drinking 15 oz of cranberry juice cocktail .

    Since Sobota’s initial report, several studies have confirmed that the presumed efficacy of cranberry in preventing UTI is related to its antiadherent properties. It is now known that E. coli, the most common cause of UTI, have hairlike fimbria that protrude from their surface. The fimbriae produce 2 adhesins that attach to receptors on uroepithelial cells .

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    How To Take Cranberry Juice For Uti:

    If you wish to use cranberry juice to treat UTI then you must take it 114 to 296ml or in doses of 4 to 10 oz. of pure juice, a day. Since cranberry juice is very sour the cranberry juice which is available commercially contains added sweeteners. You should therefore purchase that brand which has the lowest amount of added sugar.

    What Juice Is Good For Kidney Function

    The potassium content of grapes, apples, and cranberries is lower than that of oranges and orange juice, so they are good substitutes. Potassium is a major component of orange juice and should be consumed only on a renal diet. Instead of grapes, apples, cranberries, or their juices, try grapes, apples, or cranberries.

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    Cranberries For Preventing Urinary Tract Infections

    Cranberries have been used to prevent urinary tract infections . Cranberries contain a substance that can prevent bacteria from sticking on the walls of the bladder. This may help prevent bladder and other UTIs. This review identified 24 studies comparing cranberry products with control or alternative treatments. There was a small trend towards fewer UTIs in people taking cranberry product compared to placebo or no treatment but this was not a significant finding. Many people in the studies stopped drinking the juice, suggesting it may not be an acceptable intervention. Cranberry juice does not appear to have a significant benefit in preventing UTIs and may be unacceptable to consume in the long term. Cranberry products were also ineffective , possibly due to lack of potency of the ‘active ingredient’.

    Cranberries have been used widely for several decades for the prevention and treatment of urinary tract infections . This is the third update of our review first published in 1998 and updated in 2004 and 2008.

    All randomised controlled trials or quasi-RCTs of cranberry products for the prevention of UTIs.

    Two authors independently assessed and extracted data. Information was collected on methods, participants, interventions and outcomes . Risk ratios were calculated where appropriate, otherwise a narrative synthesis was undertaken. Quality was assessed using the Cochrane risk of bias assessment tool.

    Searching For An Alternative Treatment

    Cranberry Juice for Urinary Tract Infections: What does the Evidence Say?

    Urinary tract infections plague women of all ages, and as men age, they too become increasingly susceptible. UTIs, as they are commonly known, occur when bacteria infect the urinary tract. Symptoms include feeling the need to urinate despite having an empty bladder, pain or burning while peeing, frequent urination, low fever and cloudy or bloody urine.

    The body can sometimes flush out an infection on its own, according to the US Centers for Disease Control and Prevention, but an infection may cause discomfort and could spread to the kidneys, becoming serious.

    Among nursing home residents, UTIs are the most commonly diagnosed infection. Still, its a difficult diagnosis to make since bacteria in the urine can come without symptoms. Research has showed that up to half of all women living in nursing homes test positive for bacteriuria, or bacteria in the urine, even if they dont experience symptoms of an infection. Pyuria is present in 90% of residents with bacteriuria.

    To treat infections, doctors usually prescribe antibiotics. Yet the germs causing these infections are becoming less susceptible to these drugs, and infections do not always go away easily.

    One of the first studies that showed that cranberry juice was effective in older women living in nursing homes and assisted-living facilities was published in 1994, Juthani-Mehta said.

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    Is Ocean Spray Cran Apple Juice Healthy

    Ocean spray cran apple juice is a healthy drink that is made from real fruit juice and has a light and refreshing taste. It is also a good source of vitamin C, which helps to keep your body healthy. Ocean spray cran apple juice is a great drink for anyone looking for a healthy way to enjoy their favorite fruit.

    Commercially Available And Fresh Cranberry Juice Significantly Reduce Bacterial Counts In Infected Bladders

    The mice in the control groups drinking only water were infected with a median of 5.4 × 104 CFU per g bladder at sacrifice day 7 after inoculation . Treatment with both commercially available Cranberry Juice Cocktail and fresh cranberry juice reduced the CFU in the bladder by 65% and 47% , respectively . Also treatment with the hydrophilic fraction of cranberry juice decreased CFU in the bladder by 44% whereas treatment with the ethanolic fraction of cranberry juice had no effect. Only very few mice had kidney infection and the bacterial counts were low prohibiting analysis of treatment effect in the kidneys .

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    Why Do Girls Drink Cranberry Juice: The Science Behind This Well

    Cranberry juice has grown in popularity over the years. Its been called a miracle drink, and its been said to have healing properties for everything from bladder infections to yeast infections. But what is this fruit that garners so much attention? Cranberries are a type of berry that grow on low-lying vines in boggy alluvial soils.

    They have a sour taste and a white, seedy center. Native Americans used to pick cranberries by hand and boil them with sugar for use during winter months. Today, we can find cranberries in a variety of foods and drinks, including cranberry juice cocktails, pastries, sauces, jams, jellies, muffins, cakes even wine!

    In this article we answer all your questions about why girls drink cranberry juice.

    Implications For Practice And Research

    Urinary Tract Infections Objective 8
    • Not all cranberry products contain enough active proanthocyanidins for clinical efficacy. Consumers should look for products containing 36mg of PACs.

    • Cranberry is nearly as effective as low-dose antibiotics for urinary tract infection prevention in women and children and does not cause antibiotic resistance.

    • If cranberry products are being recommended to patients, conclusions of this one review do not provide sufficient reasons to change current practices.

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    Cranberry Juice Wont Prevent Bladder Infections

    Its a myth that cranberry juice can cure bladder infections, the Daily Mail reported today. The story was based on a large review of research that looked at the effectiveness of cranberry juice and cranberry products such as capsules, in preventing bladder and other urinary tract infections , which are most common in women.

    The use of cranberry juice to protect against infection was first thought to have originated with Native Americans. It is now a popular home remedy, often recommended to women by their doctors to help prevent infections on the basis of previous research that suggested it could be helpful.

    The theory is that cranberry juice contains substances that help prevent bacteria from sticking to the wall of the urinary tract. However, this new widely reported study found that overall, cranberry products did not reduce the occurrence of UTIs, such as cystitis, when compared with placebo, water or no treatment at all.

    This updated review comes from the respected Cochrane Collaboration and its results are likely to be reliable. It suggests that while cranberry juice may be of small benefit to some women, it would need to be consumed in such large quantities as to make it unacceptable to many as a remedy.

    Other cranberry products were also found to be ineffective, possibly due to the lack of potency of the active ingredients. Other methods women can use to reduce the risk of developing a UTI include drinking plenty of fluids and practising good hygiene.

    May Help Prevent Utis In Some People

    Some research suggests that cranberry juice and cranberry supplements may reduce the risk of UTIs in certain populations.

    One review of 7 high quality studies that included 1,498 healthy women found that taking cranberry juice and cranberry supplements reduced the risk of UTI recurrence by 26% .

    Another review concluded that cranberry products seem to prevent UTIs in women, but that they arent helpful for this purpose among people who are at an increased risk of contracting UTIs .

    Findings from other studies have also suggested that cranberry products, including cranberry juice, may help prevent UTIs from coming back in a few different populations, including (

    • women with a history of UTIs
    • older adults in nursing homes
    • otherwise healthy children

    Some findings also suggest cranberry juice capsules may help reduce UTIs in women whove undergone gynecological surgeries during which a catheter was placed in their urethra to empty their bladder .

    Its important to note that cranberry extract, which is different from cranberry juice, has more evidence supporting its ability to help prevent UTIs from recurring in certain populations.

    This is because cranberry supplements are a more concentrated source of the active compounds thought to be helpful in UTI treatment.

    Proanthocyanidins are a type of polyphenol compound that is naturally concentrated in cranberries.

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