Botox Treatment For Overactive Bladder
Are you experiencing a sudden urge to urinate more often than usual? Do you find yourself unable to make it to the restroom in time? Or are you experiencing side effects from certain medications that impact your bladder? If so, you might be wondering if Botox treatment for Overactive Bladder may be the right solution for you.
Botox Works As Well As Nerve Stimulator For Incontinence Study
An injection of Botox works about as well as a surgically implanted device to help women with very severe incontinence, researchers reported Tuesday.
Its good news for women with severe urge incontinence, who can choose between treatments based on preference, said Dr. Cindy Amundsen of Duke University, who led the study.
What we have learned from the study is the treatments are both good and it will just help inform physicians and patients who are trying to make a decision between these two therapies, Amundsen said.
We are actually not surprised that there isnt a big difference between the two because both therapies are effective at relaxing the overactive bladder muscles.
Women can choose between a surgical procedure, which is more expensive at first, versus regular Botox injections, which are less costly and less invasive but which could add up over time, Amundsen said.
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The team studied women with severe incontinence who could not be helped with drugs or other treatments. The women in the study had to suffer at least six episodes of incontinence over three days.
The Botox injections freed 20 percent of the women in the study of incontinence, compared to 4 percent who had a nerve stimulator implant, Amundesen and colleagues reported in the Journal of the American Medical Association.
Incontinence may sound funny, but its no joke, the researchers said.
How Effective Is Botox
Botox has been shown to be an effective treatment option for bladder problems. In studies, people who received Botox injections for overactive bladder symptoms saw improvements in certain symptoms, such as frequent urination, in the 12 weeks after treatment. People also noticed an increase in the amount released during urination.
Another improvement that people using Botox for OAB symptoms noticed after receiving the injections was fewer episodes of urinary incontinence. In studies, these improvements lasted from 19 to 24 weeks.
In other studies of Botox used for OAB symptoms in adults, people reported improvements in their symptoms and in their quality of life.
Two studies looked at adults who had urinary incontinence with detrusor overactivity* linked with a neurological condition. These studies found that people who received Botox injections had fewer episodes of urinary incontinence. These improvements lasted 42 to 48 weeks for at least half the people in the study.
If you have questions about the results you can expect with this drug, talk with your doctor.
* This refers to overactivity of the detrusor muscle, which is the muscle that lines the bladder.
- overactive bladder symptoms in adults
- urinary incontinence with detrusor overactivity* linked with a neurological condition such as multiple sclerosis or a spinal cord injury, in adults and children ages 5 years and older
* This refers to overactivity of the detrusor muscle, which is the muscle that lines the bladder.
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How Do Bladder Botox Injections Work
Botox injections are not just for wrinkles on your face. They also can be used to help if you have ongoing bladder continence issues. Botox is one option to treat urge incontinence or overactive bladder in people who have not had success with other treatment options.
Urinary incontinence is common and can impair your social, physical or mental well-being. Approximately 17% of women and 3% to 11% of men suffer from urge incontinence at some point in their lives.
Urge incontinence is the unintentional loss of urine caused by your bladder contracting.
About Oab And Detrusor Overactivity
OAB and detrusor overactivity can both cause trouble with urination. With these conditions, you may have involuntary spasms in your bladder muscles, even when you dont actually need to urinate.
The exact cause of OAB isnt known. But some possible factors or causes may include:
- consuming caffeine, alcohol, or other bladder irritants
- taking medications that increase urine output
- other bladder problems, such as bladder stones
- not completely emptying the bladder
Detrusor overactivity can be linked with neurological conditions such as MS or a spinal cord injury. These neurological conditions affect how your brain communicates with the rest of your body. In some cases, they can cause bladder problems such as detrusor overactivity.
What Is Botox And How Does It Work
BotoxÂ® is a pharmaceutical preparation of the botulinum toxin type A produced by the bacterium Clostridium botulinum, which has muscle relaxant properties. It is usually used in MS for two reasons.
The first reason is for the relief of focal muscle spasticity and is usually used in conjunction with stretching and physiotherapy.
The second reason Botox is helpful in MS, is for the treatment of urinary incontinence due to overactivity of the detrusor muscle in the bladder. There are strict criteria to guide selection of the most suitable patients for this procedure, where clinical trials have shown significant improvements in quality of life and incontinence episodes.
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What To Expect After Bladder Botox Injection
Its important to note that the injections wont take immediate effect. While some people notice a difference within a few days, people with urinary incontinence can expect to wait one to two weeks before seeing the number of daily leakage episodes come down. According to the makers of Botox, you should expect to see full results by week 12.
Its also important to remember that this treatment isnt a cure. You may still experience occasional issues with urinary incontinence or overactive bladder, and the effects of the injections will wear off over time and need to be repeated. More on that later.
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How Is The Botox Treatment For Overactive Bladder Performed
Botox Treatment for Overactive Bladder may be undertaken in the following manner:
- The procedure is performed by applying a local anesthetic agent to the pelvic site. Occasionally, the individual may be administered general anesthesia
- The inside of the urinary bladder is explored by the urologist by inserting a cystoscope, which is a thin tube having a tiny camera at its end
- Botox injections are then administered to the targeted site , through the thin tube several injections may be given during a session
- Following the procedure, the individual is placed under observation for a period of time, until they first pass urine. In some cases, hospitalization may be necessary and the patient may be asked to stay overnight
The Botox Treatment Procedure
Prior to the day of treatment, the patient will be given an antibiotic to reduce the chances of a urinary tract infection . Before treatment, a test will be completed to make sure the patient does not have a UTI. If they do have one, the treatment will be rescheduled.
At Urology Associates Botox is administered under general anesthesia or sedation in an ambulatory surgical center. The doctor performs a cystoscopy by inserting a cystoscope through the urethra, the opening where urine exits the body. Botox is given through the cystoscope by a series of quick injections into specific areas of the patients bladder muscle.It can take 24-72 hours before the Botox takes effect, but in rare cases it may take longer.
About 6 out of every 100 patients require a catheter after the treatment. If this is needed, the doctor will discuss the catheter process including cleaning prior to treatment. This is a smaller catheter than those found in hospitals and can be easily hidden.
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Dosage For Upper And Lower Limb Spasticity
The typical dosage of Botox for upper limb spasticity in adults ranges from 75 units to 400 units. For lower limb spasticity in adults, the typical dosage of Botox ranges from 300 units to 400 units. Dosages for limb spasticity in children are described below in the Pediatric dosage section.
The exact Botox dosage for this use depends on the size, location, and number of muscles affected. It also depends on the severity of your spasticity. The total recommended dosage for spasticity is divided into multiple injections into affected muscles.
Botox treatment for spasticity may be repeated when the drugs effect wears off. But each treatment session must be at least 12 weeks apart.
The dosage youre given for spasticity may change each time you have a session for Botox injections. Your dosage will vary depending on how your body responded to previous injections.
Note: To learn more about upper and lower limb spasticity, see the Other uses for Botox section above.
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Botox Bladder Injection Treats Overactive Bladder And Leakage
While Botox is best known for its cosmetic use as a treatment for lines and wrinkles on the face, it has been FDA-approved for a number of uses including treatment of overactive bladder . Botox essentially paralyzes the bladder muscle so that it no longer spasms. Botox injections also interfere with the way muscles and nerves talk to each other. The medication disrupts any inappropriate signals going from the bladder to the brain, which might be telling the brain that the bladder is full when its really not.
OAB is a common problem in men and women as they get older. Women in particular may have OAB symptoms associated with pregnancy and .
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Dr Oz: Urge Incontinence
Dr Oz shared some of the newest developments in medical research that offer promising results for patients. These treatments could put an end to troubling symptoms that have endured for years. Find out about the advances in Cardiac Catheterization and read on to learn about the Urge Incontinence bladder Botox cost.
Are Botox Bladder Injections Covered By Insurance
Botox is covered by most insurance plans, including Medicare. However, insurance carriers vary as do individual patient needs. Before receiving Botox bladder injections, be sure to check with your insurance provider about coverage. Eligible patients can save on out-of-pocket costs not covered by insurance.
1Botox for Overactive Bladder. Accessed August 24, 2018.
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What Is Botulinum Toxin
Botulinum toxin is a natural, purified protein, which has the ability to relax the muscle into which it is injected. Botulinum toxin type A is produced by a bacteria similar to the way that penicillin is produced by a mould.
While there are many different types and brands of Botulinum toxin, BotoxÂ® is the brand that has been most widely researched for use in the urinary tract.
Botulinum toxin has been widely and safely used for over 20 years in other conditions such as the treatment of squint, muscle spasm, recurrent migraines and more recently by cosmetic surgeons in the treatment of facial wrinkles.
How Does Botox Work
Botox helps relieve the symptoms of bladder problems by promoting bladder control.
The detrusor muscle that lines the bladder plays an important role in bladder control. When the muscle relaxes, the bladder can fill with urine. When youre urinating, the muscle contracts to release urine.
If you have overactive bladder symptoms or detrusor overactivity, your bladder muscles spasm involuntarily . Botox is injected into the detrusor muscle to block the nerve signals to the muscle. This helps control the muscles contractions.
Below are answers to some commonly asked questions about Botoxs use in treating bladder conditions.
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Comparing Bladder Botox To Similar Treatments
Botox can have multiple benefits for overactive bladder or incontinence. This can be the ideal treatment for people of all ages. For older patients, this may be preferable to surgery since it will take less of a toll on the body.
Botox injections for the bladder are comparable in cost with most insurance coverages for oral medications, InterStim or percutaneous tibial nerve stimulation .
Below we highlight the pros and cons of Botox compared to other treatment options.
How Is Botox Treatment Performed
Botox is injected directly into the bladder muscle through an instrument placed into the bladder called a cystoscope. After being positioned on an examining table, anesthetic jelly is passed into the urethra, then a catheter is passed into the bladder, and the urine is drained. Through this catheter, a local anesthetic solution is placed into the bladder to numb its lining. A small flexible needle is then introduced through the cystoscope to perform the injections. Anywhere from 10 to 30 injections are made into the bladder, and at each site a small amount of Botox solution is injected.
The procedure is usually performed on an outpatient basis, meaning that no overnight hospital stay is required. In most cases, only local anesthetic is required however, some doctors may also give sedative medication, and some prefer to perform the procedure with the patient under spinal or general anesthetic depending on the situation. Typically, the procedure takes only 10 to 30 minutes. Antibiotics are given before the procedure.
Who Should Undergo Botox Bladder Injections
Although Botox for the bladder is effective in treating incontinence, it is not recommended for everyone. The ideal candidates are female urology patients who do not show successful results from other treatments such as antispasmodic medication or fluid intake and pelvic floor exercises.
Patients would first need to undergo such steps or medication before a urologist allows them to receive Botox injections. For the best results, patients should receive more injections roughly every six months.
Botox May Beat Neural Stimulation For Urge Incontinence But Has Risks
DURHAM, N.C. — When women suffer from bladder incontinence, the urge to urinate can come on suddenly and sometimes uncontrollably, leading to leakage. Patients looking for relief can initially opt for first- and second-line therapies such as drinking fewer liquids or caffeinated beverages, pelvic floor muscle training, and medication.
If those treatments prove inadequate however, patients may seek more invasive options, including a form of nerve stimulation called sacral neuromodulation , or a bladder injection of botulinum toxin, which is sold as Botox.
A head-to-head comparison of sacral neuromodulation and botulinum toxin led by a Duke Health researcher shows that Botox provides more daily relief for women, but might also be associated with more adverse events.
The findings were Oct. 4 in the Journal of the American Medical Association .
An injection of botulinum toxin in the bladder muscle works to address urgency urinary incontinence by relaxing the overactive bladder muscles that cause the condition. A sacral neuromodulation implant does the same thing by sending electrical pulses to nerves in the spine.
The study involved 381 women from nine U.S. medical centers who recorded at least six urgency incontinent episodes over three consecutive days and had not improved with other treatments.
Botulinum toxin participants also reported a greater reduction in bothersome symptoms, higher satisfaction with treatment, and a greater likelihood of endorsing the treatment.
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What Other Warnings Should I Know About
In addition to the boxed warning described above, Botox has other warnings. If any of the following medical conditions or other health factors apply to you, talk with your doctor before using Botox:
- if you have a history of side effects from any botulinum toxin product
- if you have a condition that affects your muscles or nerves, such as amyotrophic lateral sclerosis or myasthenia gravis
- if you currently have or have a history of breathing problems, such as asthma or emphysema
- if you currently have or have a history of problems with swallowing
- if you currently have or have a history of bleeding disorders
- if you have a urinary tract infection
- if you have trouble emptying your bladder on your own
- if you have surgery planned
- if youre pregnant or breastfeeding
- if youve had an allergic reaction to the drug or any of its ingredients
Botox injections may interact with other medications youre taking. Tell your doctor about all drugs youre using, including prescription and over-the-counter products.
Also, tell your doctor if you:
- have received other botulinum toxin products or injections in the past
- have recently received antibiotics by injection
- are taking an allergy or cold medication
- use sleep medication
What Are The Side Effects Of Botox
The lists below include some of the main side effects that have been reported in people using Botox. For information about other possible side effects of the drug, talk with your doctor or pharmacist.
Note: After the Food and Drug Administration approves a drug, it tracks and reviews side effects of the medication. If youd like to notify the FDA about a side effect youve had with Botox, visit MedWatch.
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Are There Any Long
In general, you may have side effects within the first week of receiving Botox injections. Most of the time, these side effects are temporary, but sometimes, side effects can last for several months or longer.
But possible long-term side effects of Botox can include: