How To Cope With Side Effects
What to do about:
- feeling sick â try taking mirabegron with a meal or snack. It may also help if you stick to simple meals and avoid rich or spicy food.
- constipation â eat more high-fibre foodsâ¯such as fresh fruit, vegetables and cereals, and drink plenty of water.â¯Try to exercise more regularly, for example, by going for a daily walk or run. If this does not help, talk to your pharmacist or doctor.â¯Watch this short video about how to treat constipation.
- diarrhoea â drink lots of fluids, such as water or squash, to avoid dehydration. Signs of dehydration include peeing less than usual or having dark strong-smelling pee. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.
- urinary tract infection â if you think you have a UTI, ask a pharmacist or doctor to recommend a treatment. Tell them that you are taking mirabegron.
- headache â make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask a pharmacist to recommend a painkiller. Talk to your doctor if the headaches continue or are severe.
- feeling dizzy â stop what you’re doing and sit or lie down until you feel better. Do not drive, ride a bike or operate machinery until it passes. If you are still having dizzy spells after a week, speak to your doctor.
- fast heart rate â lie down and try to relax. This is usually nothing to worry about and will pass. Contact 111 if your heart beat does not slow down after resting, or if you have chest pain.
Kegels For Stress Incontinence
Many women experience bladder leakage with coughing and sneezing with stress urinary incontinence.
The key functional training technique to practice is called The Knack. This pelvic floor exercise technique involves contracting your pelvic floor muscles immediately before and during the activities that cause your stress incontinence for example coughing, sneezing or laughing.
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Pharmacologic Agents That Cause Urinary Incontinence
A variety of drugs have been implicated in urinary incontinence, and attempts have been made to determine the mechanism responsible based upon current understanding of the processes involved in continence and the transmitters that play a role. Each of the processes described previously can be manipulated by pharmacologic agents to cause one or more types of incontinence.
The drugs commonly pinpointed in urinary incontinence include anticholinergics, alpha-adrenergic agonists, alpha-antagonists, diuretics, calcium channel blockers, sedative-hypnotics, ACE inhibitors, and antiparkinsonian medications. Depending upon the mode of action, the effect may be direct or indirect and can lead to any of the types of incontinence. Taking these factors into account, it is important to consider a patients drug therapy as a cause of incontinence, particularly in new-onset incontinence patients and in elderly patients, in whom polypharmacy is common.11,12
On the other hand, a pharmacologic agent or any other factor that results in chronic urinary retention can lead to a rise in intravesical pressure and a resultant trickling loss of urine. In this way, drugs that cause urinary retention can indirectly lead to overflow incontinence.2
It is useful to note that many antidepressants and antipsychotics exhibit considerable alpha1-adrenoceptor antagonist activity.1
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Myrbetriq May Cause Serious Side Effects Including:
Increased blood pressure: cause your blood pressure to increase or make your blood pressure worse if you have a history of high blood pressure. You and your doctor should check your blood pressure while you are taking Myrbetriq. Call your doctor if you have increased blood pressure.
Inability to empty your bladder : chances of not being able to empty your bladder if you have bladder outlet obstruction or if you are taking other medicines to treat overactive bladder. Tell your doctor right away if you are unable to empty your bladder.
Angioedema: Myrbetriq may cause an allergic reaction with swelling of the lips, face, tongue, or throat with or without difficulty breathing. Stop using Myrbetriq and go to the nearest hospital emergency room right away.
- The 52week Myrbetriq Safety Study Explained:
- The study involved 812 patients taking Myrbetriq 50 mg 1 time a day for up to 52 weeks. Patients reported their side effects. Another group of 812 patients were given the standard treatment , and they reported their side effects.
- Most common side effects reported by greater than 3% of patients treated with Myrbetriq 50 mg 1 time a day in Study 4.
- What is an Active Control for clinical studies?
- This is the name for the standard treatment people with a certain condition are given.
Click on the side effect to see the percentage of patients who were affected
Percentage of patients who experienced side effect
- Myrbetriq 50 mg
Percentage of patients who experienced side effect
How Is Overactive Bladder Diagnosed
A healthcare provider can diagnose overactive bladder by reviewing your symptoms and conducting a physical examination of the organs around your pelvis and rectum. They may ask you questions such as:
- What are your symptoms?
- How long have you had these symptoms?
- Do you have a family history of overactive bladder?
- What over-the-counter and prescription drugs do you take?
- What kinds of fluids do you drink during the day?
- What time of day do you drink certain fluids?
- What do you eat during the day?
They may also refer you to a urologist. A urologist is a doctor who specializes in diseases and conditions that affect your urinary tract and reproductive system.
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What Is The Bottom Line About This Health Issue
If you have trouble with leaking urine, know that you are not alone many women suffer from urinary incontinence. There is no shame in discussing this problem with your doctor or an incontinence professional . The real harm is in ignoring incontinence. Non-drug treatments, such as healthy lifestyle changes or pelvic floor exercises, should be the first choice. Once you start adopting healthy behaviors, sticking to these good habits will serve you well in the long run.
Currently there are no effective medications for women with stress incontinence. In contrast, women with urgency incontinence have good evidence that several medications can be helpful. There are eight drug choices available and women can make informed decisions with their doctors. We “urge” you to take into account the balance between benefits and harm for each of eight available drugs and to make informed treatment decisions after discussions with incontinence professionals.
Dont Ignore Your Diet
While you may have never thought about it, our bladder and bowel often work in synchronization.
When the bowel is full it starts putting pressure on the empty bladder, making you feel like you need to pee.
So, to steer clear from this situation and prevent an indirect urinary urgency from building up, it is always better to add food items such as green leafy vegetables, fresh fruits, and beans to your diet that keep your bowel relaxed and constipation-free.
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When You Should See A Health Care Professional
You shouldnt have to wear a pad to soak up urine every day. Also ask yourself these questions:
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Is the urge to urinate interfering with your work because of leaking or frequent bathroom breaks?
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Do you map out where bathrooms are when you run errands?
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Is incontinence interfering with your sex life or intimacy with your partner?
These are all signs of a problem, and that it may be time for you to talk with a gynecologist.
Mind Your Pees And Queues
AkaMisery explained that she felt a constant pressure like she had to pee. As soon as she emptied her bladder, the feeling built up again. There was no burning, her urine was a normal colour and there was no smell. This sort of symptom can have lots of causes. Urine infections and sexually transmitted infections head the list, followed by bladder conditions such as stones and – rarely – tumours. AkaMisery had lots of tests to rule out these conditions and did the rounds of various doctors who she really didn’t find very helpful.
Middlechild79 posted on the board that she had had similar symptoms and wondered if the problem was overactive bladder . I agree that – having ruled out other causes – it’s very likely that this is the diagnosis.
OAB occurs when the bladder squeezes suddenly without you having control and when the bladder is not full. It’s sometimes called an irritable bladder or detrusor instability . OAB can cause major disruption to a person’s life. Simple activities, such as going out, shopping or queuing, can become a nightmare.
OAB can occur after a stroke, with Parkinson’s disease, in multiple sclerosis or after a spinal injury. However, in most cases no cause can be found. It’s then called overactive bladder syndrome.
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Approved For Combination Use
For adults with overactive bladder symptoms of urgency, frequency and leakage, Myrbetriq is FDAapproved for use in combination with solifenacin succinate. Ask your doctor if this combination treatment may be right for you.
What is MYRBETRIQ? MYRBETRIQ is a prescription medicine for adults that can be used alone or with solifenacin succinate to treat the following symptoms due to a condition called overactive bladder:
- Urge urinary incontinence: a strong need to urinate with leaking or wetting accidents
- Urgency: a strong need to urinate right away
- Frequency: urinating often
How should I take MYRBETRIQ
- If your doctor prescribes MYRBETRIQ and solifenacin succinate together, you should take 1 MYRBETRIQ tablet and 1 solifenacin tablet at the same time, 1 time a day.
- You should take MYRBETRIQ with water and swallow the tablet whole.
- Do not chew, break, or crush the tablet.
- You can take MYRBETRIQ with or without food.
- You can take MYRBETRIQ and solifenacin succinate together with or without food.
- If you miss a dose of MYRBETRIQ tablets, take it as soon as possible. If it has been more than 12 hours since taking the last dose of MYRBETRIQ tablets, skip that dose and take the next dose at the usual time.
- If you take too much MYRBETRIQ tablets, call your doctor or go to the nearest hospital emergency room right away.
The most common side effects of MYRBETRIQ, when used with solifenacin succinate, include:
Botox Injection For Bladder Problems
Botox injection has recently been approved by the Food and Drug Administration for the treatment of overactive bladder for patients who have failed to respond to standard therapy with anticholinergic medications.
Overactive bladder is a type of urinary incontinence caused by overactivity of the muscles in the bladder, causing frequent squeezing of the bladder and, thus, frequent urge to urinate. Botox can be injected into the bladder directly through a cystoscope .
Common side effects of Botox injection may include incomplete emptying, urinary tract infection, and painful urination.
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Oxybutynin Gel May Cause Side Effects Tell Your Doctor If Any Of These Symptoms Are Severe Or Do Not Go Away:
- difficulty breathing or swallowing
- frequent, urgent, or painful urination
Oxybutynin gel may cause other side effects. Call your doctor if you have any unusual problems while you are using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s MedWatch Adverse Event Reporting program online or by phone .
What Is The Usual Length Of Treatment
Duloxetine is usually given for about a month after this, you are assessed to see if your symptoms have improved. If your symptoms have improved, duloxetine may be continued and you are assessed every few months to see if it is still working. Your doctor may decide to stop treatment if your symptoms do not improve. If your doctor thinks that you should stop taking duloxetine you should do this slowly – for example, over 1-2 weeks. You should never stop taking this medicine suddenly. This is because you can have withdrawal symptoms such as dizziness, feeling sick and headaches.
For antimuscarinics, a common plan is to try a course of medication for a month or so. If it is helpful, you may be advised to continue for up to six months or so and then stop the medication to see how symptoms are without the medication. Symptoms may return after you finish a course of medication. If you combine a course of medication with bladder training, the long-term outlook is better and symptoms may be less likely to return when you stop the medication. The need for continuing antimuscarinic medicine therapy should be reviewed every 4-6 weeks until symptoms stabilise and then every 6-12 months.
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Myrbetriq For Older Adults
- Studies showed that there were no overall differences in the safety and effectiveness of Myrbetriq for adults over age 65 versus under age 65
- Older adults taking Myrbetriq do not need to take a different dose
- Myrbetriq works in the body in similar ways for older and younger adults
The American Geriatrics Society Beers Criteria® is a list of medicines that older adults should usually avoid. Myrbetriq is not on that list.
Do Pelvic Floor Muscle Exercises
Strong pelvic floor muscles hold in urine better than weak muscles. You can strengthen your pelvic floor muscles by doing Kegel exercises. These exercises involve tightening and relaxing the muscles that control urine flow. Researchers found that women who received pelvic floor muscle training had fewer leaks per day than women who didnt receive training.6 You should not do pelvic floor exercises while youre urinating.
Men can also benefit from pelvic floor muscle exercises. Strengthening these muscles may help a man leak urine less often, especially dribbling after urination.
A health care professional, such as a physical therapist trained in pelvic floor therapy, can help you get the most out of your Kegel exercises by helping you improve your core muscle strength. Your core includes your torso muscles, especially the lower back, pelvic floor muscles, and abdomen. These muscles keep your pelvis lined up with your spine, which helps with good posture and balance. Your physical therapist can show you how to do some exercises during daily activities, such as riding in a car or sitting at a desk.
You dont need special equipment for Kegel exercises. However, if you are unsure whether you are doing the exercises correctly, you can learn how to perform Kegel exercises properly by using biofeedback, electrical stimulation, or both. Biofeedback uses special sensors to measure muscle contractions that control urination.
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How Well Do Medicines For Urinary Urgency And Incontinence Work
For duloxetine, one study showed that in about 6 in 10 women who took duloxetine, the number of urine leakages halved compared to the time before they took the medication. Therefore, on its own, duloxetine is not likely to cure the incontinence but may help to make it less of a problem. However, duloxetine in addition to pelvic floor exercises may give a better chance of curing the incontinence than either treatment alone.
Antimuscarinic medicines are all thought to be as effective as each other. They may improve symptoms in some cases but not in all. The level of improvement varies from person to person. You may have fewer toilet trips, fewer urine leaks and less urgency. However, it is uncommon for symptoms to go completely with medication alone.
How Do I Control Urges When Resetting My Bladder
Controlling your urges is a key step in resetting your bladder. The following strategies may help:
- Stop what youre doing and stay put. Stand quietly or sit down, if possible. Remain as still as possible. When youre still, its easier to control your urges.
- Squeeze your pelvic floor muscles quickly several times . Dont fully relax in between Kegels.
- Relax the rest of your body. Take several deep breaths to help you let go of any tension.
- Concentrate on suppressing your urge to pee.
- Wait until the urge goes away.
- Walk to the bathroom at a normal pace. Dont rush. Continue squeezing your pelvic floor muscles quickly while you walk.
Patience is important. Retraining your bladder usually takes at least six to eight weeks to see results. Talk to a healthcare provider if you have any questions or arent happy with your progress. They may prescribe medications for you to take while youre resetting your bladder to help you achieve the best outcome.
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Causes Of Urge Incontinence
The urgent and frequent need to pass urine can be caused by a problem with the detrusor muscle in the wall of the bladder. The detrusor muscles relax to allow the bladder to fill with urine, then contract when you go to the toilet to let the urine out.
Sometimes the detrusor muscle contract too often, creating an urgent need to go to the toilet. This is known as having an âoveractive bladderâ. The reason your detrusor muscle contracts too often may not be clear, but possible causes include:
- drinking too much alcohol or caffeine
- poor fluid intake this can cause strong, concentrated urine to collect in your bladder, which can irritate your bladder and cause symptoms of overactivity
Stopping these medications, if advised to do so by a doctor, may help resolve your incontinence.
Nay On Horsetail Cranberries
Horsetail , an ancient plant that resembles a bristly tail when dried, may produce a mild diuretic effect. The goal of OAB treatment is control over random bladder spasms, not increased urine flow. The diuretic effect and lack of studies mean you should cross horsetail off your list if youre looking for help for OAB.
The same is true for cranberries. The fruit is very acidic, which may aggravate the symptoms of OAB. Cranberries may change the way bacteria adheres to the bladder in a urinary tract infection, but bacteria isnt involved in involuntary contractions that cause OAB.
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