Common Side Effects With Antibiotic Use
Each antibiotic is responsible for its own unique list of side effects, and the list is usually extensive. Be sure to discuss your individual antibiotic side effects with your healthcare provider. However, there are side effects that are common to most antibiotics, regardless of class or drug:
What Is A Uti
A urinary tract infection occurs when bacteria enter the urethra and infect the urinary tract. There are many different parts of the urinary tract that can become infected, and the most common type of UTI is a bladder infection. UTIs may cause discomfort, pain, and burning sensations. They can typically be treated with antibiotics.
People of any sex or age can get a UTI, but it is much more common for women to get UTIs. You are also more likely to get a UTI if you are sexually active, pregnant, or if you have had a UTI before. Symptoms such as pain or burning when urinating, pressure in the low belly, an urge to urinate often, and fatigue and shakiness can all be signs of a UTI. Speak with your healthcare provider if you think you may have a UTI.
Causes Of Utis And Bladder Infections In Men
Women are more likely to get urinary tract infections and bladder infections than men because they have a shorter urethra located closer to their rectum.
For them, sexual activity or even wearing a pair of underwear for too long can cause bacteria like E. coli to come in contact with the urinary tract.
Men can get UTIs too, but in their case, its usually due to genetics, prostate changes with age, or an abnormal immune response. STDs such as chlamydia are another frequent cause of UTIs in men.
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Bri Nutrition 3x Strength Crangel Power Plus
Coming in at third on the list of the most popular UTI remedies is BRI Nutrition Cranberry Concentrate Extra Strength. The main difference between this product and others on the list is that it includes lingonberry into its formula, which is an all-natural ingredient that helps fight off UTI.
While its not the cheapest option on the list, it has proven to be quite effective on some people. That said however, its worth saying that BRI Nutrition Cranberry Concentrate Extra Strength has been said to be ineffective on others.
Based on consumer reviews, some people failed to experience any sort of benefit from the product, which makes it a questionable choice for some buyers. Nonetheless, it has been said to work wonders for others, so you should keep in mind that the results always depend on how the system takes to the product.
When To See A Doctor
As soon as you notice symptoms consistent with a urinary or bladder infection, contact your doctor. The treatment process should be quick and easy, but the longer you wait, the more complicated and painful things may become.
Untreated UTIs and bladder infections can lead to kidney infections. The symptoms of kidney infections overlap with bladder infections but are more intense and may include severe abdominal pain, one-sided or overall back pain, nausea, vomiting, fever, and chills. To avoid this situation, take a proactive approach to your UTI treatment and seek out a medical providers advice.
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Still Unsure Try An At Home Uti Test
At home tests are a great way to detect a UTI before going to see your doctor. Some, like AZO Test Strips®, are the same urinary tract infection tests used in many doctors offices. The most reliable, over-the-counter UTI home test available, AZO Test Strips® offer two UTI tests in one including both Leukocyte and Nitrite tests. These tests performed together are more effective for detecting a UTI than testing for nitrite alone.
If you get a positive result, its time to call your doctor with the results. If your result is negative but you are experiencing symptoms, you should still call your doctor. A small number of people may not have detectable nitrites even though an infection is present.
How The Uti Home Screening Test Works
The vH essentials UTI Home Test is a quick and simple test that detects urinary nitrite and the presence of protein in the urine. Subsequent to the application of urine, color differentiation determines whether the test is positive or negative. For example, a color change from white to pink and from yellow to green develops when nitrites and proteins are detected, respectively. A deeper color signifies higher concentrations of proteins and nitrites.
The accuracy of this test is limited by certain circumstances that may skew the results. For example, false-negative results may be observed following high consumption of ascorbic acid, antibiotics, or fruit juices, or if the urine is not in the bladder for at least 4 to 6 hours. False positives may present if the urine specimen appears red due to any cause for example, recent ingestion of common UTI pain relief medication containing phenazopyradine dye or contamination with menstrual fluid. In the event of a positive nitrite or protein result, patients should contact their primary health care provider. And even if both nitrites and proteins are negative, patients with persistent symptoms need to see a health care provider for further evaluation. Patient instructions may be found in TABLE 1.
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The Status Of Phenazopyridine
In 1983, the FDA published a Drug Efficacy StudyImplementation notice with conditions for approval and marketingof all phenazopyridine products.7 These includedsulfameth-oxazole/phenazopyridine combinations ,similar combination products, and single-entity phenazopyridineproducts. The FDA presented newlyrequired statements for all phenazopyridine products intended to relievesymptoms associated with a UTI. One of the statements was critical indetermining the length of dosing: Treatment of a urinary tractinfection with phenazopyridine HCl or a combination drug productcontaining phenazopyridine HCl should not exceed 2 days because there isa lack of evidence that the combined administration of phenazopyridineHCl and an antibacterial provides greater benefit than administration ofthe anti-bacterial alone after 2 days.7
The FDA also required the following carcinogenicitystatement on all phenazopyridine labels: Long-term administration ofphenazopyridine hydrochloride has induced neoplasia in rats and mice . Although no association betweenphenazopyridine hydrochloride and human neoplasia has been reported,adequate epidemiological studies along these lines have not beenconducted.7
The best known phenazopyridine nonprescription product is Azo Standard.9Azo Standard contains 95 mg of phenazopyridine per tablet and AzoStandard Maximum Strength contains 97.5 mg of phenazopyridine.10 The dosage of both is 2 tablets 3 times daily with or after meals as needed.
What Oral Antibiotics Are Used To Treat An Uncomplicated Uti In Women
The following oral antibiotics are commonly used to treat most uncomplicated UTI infections :
Your doctor will choose your antibiotic based on your history, type of UTI, local resistance patterns, and cost considerations. First-line options are usually selected from nitrofurantoin, fosfomycin and sulfamethoxazole-trimethoprim. Amoxicillin/clavulanate and certain cephalosporins, for example cefpodoxime, cefdinir, or cefaclor may be appropriate options when first-line options cannot be used.
Length of treatment for cystitis can range from a single, one-time dose, to a course of medication over 5 to 7 days. Kidney infections may require injectable treatment, hospitalization, as well as a longer course of antibiotic, depending upon severity of the infection.
Sometimes a UTI can be self-limiting in women, meaning that the body can fight the infection without antibiotics however, most uncomplicated UTI cases can be treated quickly with a short course of oral antibiotics. Never use an antibiotic that has been prescribed for someone else.
In men with symptoms that do not suggest a complicated UTI, treatment can be the same as women. In men with complicated UTIs and/or symptoms of prostatitis are not present, men can be treated for 7 days with a fluoroquinolone . Tailor therapy once urine cultures are available.
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What Is A Uti And What Is A Bladder Infection
A urinary tract infection is an infection in your urinary system. Around 50-60% of women will experience at least one UTI in their lifetime, and an unlucky number of them get UTIs frequently. The American Urological Association estimates that 20-40% of women who have had one UTI will get another one, and 25-50% of those women will end up having at least one more after that. Men can also get UTIs, though this happens less frequently than it does in women.
UTIs occur when unwanted bacteria end up in your urinary tract and trigger inflammation. They are caused by a variety of factors, including sexual activity, poor hygiene, genetics, age, and certain types of contraceptives.
The most reliable sign of a UTI is a stinging or burning sensation with urination, though other symptoms may also occur.
A bladder infection is a type of UTI that occurs specifically in your bladder.
Think of it this way: Your urinary tract includes your urethra, bladder, ureters, and kidneys.
Your bladder is the closest organ to your urethra , so its the area of the body most commonly affected by UTIs. Doctors call inflammation in the bladder cystitis and inflammation in the urethra urethritis.
Latest Antibiotics For Utis
- Vabomere is a combination carbapenem antibiotic and beta-lactamase inhibitor. Vabomere was first approved in August of 2017.
- Vabomere is used for the treatment of adult patients with complicated urinary tract infections due to susceptible Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae species complex.
- Vabomere is given as an intravenous infusion every 8 hours. Dosage adjustments are required in patients with varying degrees of kidney impairment.
- Zemdri is an aminoglycoside antibacterial for the treatment of complicated urinary tract infections, including pyelonephritis. Zemdri was first approved in February of 2015.
- Zemdri is used against certain Enterobacteriaceae in patients who have limited or no alternative treatment options. Zemdri is an intravenous infusion, administered once daily.
See also: Treatment Options for UTIs
Treating Utis And Bladder Infections
UTIs and bladder infections are typically treated with antibiotics prescribed by a doctor. In order for the infection to go away completely, you need to take the full course of antibiotics, which lasts 3-7 days in most instances but can last longer.
It takes a bit of time for the inflammation to clear up every once the antibiotic begins working, though most people note significant improvement within 48 hours of being on the right antibiotic.
If antibiotics bother your stomach , consider taking probiotics to repopulate your good gut bacteria. This may also help you stay healthy and boost your bodys infection-fighting potential.
In the meantime, drink plenty of water so the flow of urine can help you flush out your system. You might also want to avoid sexual activity while youre recovering because its probably not going to feel great while your urinary tract is inflamed.
Otc Uti Treatment Options
UTIs are typically treated with a course of antibiotics that may run for a single day or a course of 7 days but usually lasts at an average of 1-3 days for uncomplicated urinary tract infections. However, some infections might not even need a course of antibiotics and may cease to exist. But, while treatment of UTIs without antibiotics may be a possible prospect in the future, for now, only a few equally effective OTC UTI treatments are available that can help a patient manage their symptoms. These include:
Hydration: Although not exactly an OTC UTI treatment method, hydration is still the key to treating a UTI quickly. If youve contracted a UTI, it is important to have fluids as frequently as possible so that you urinate more frequently and the harmful bacteria are flushed out of your urinary tract through natural means. This option means curing your symptoms without the use of medication.
- Probiotics: Probiotics serve as an excellent OTC UTI treatment option that helps promote digestion and immunity in your body. Probiotics restore the good bacteria present in your gut and reduce the chances of reinfection.
- Ascorbic Acid: Increasing your Vitamin C intake not only strengthens your immune system but is also a greater OTC UTI treatment option since it helps acidify the urine which may reduce the chance of reinfection.
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What About Antibiotic Resistance
Resistance rates for antibiotics are always variable based on local patterns in the community and specific risk factors for patients, such as recent antibiotic use, hospital stay or travel. If you have taken an antibiotic in the last 3 months or traveled internationally, be sure to tell your doctor.
High rates of antibiotic resistance are being seen with both ampicillin and amoxicillin for cystitis , although amoxicillin/clavulanate may still be an option. Other oral treatments with reported increasing rates of resistance include sulfamethoxazole and trimethoprim and the fluoroquinolones. Resistance rates for the oral cephalosporins and amoxicillin/clavulanate are still usually less than 10 percent.
Always finish taking your entire course of antibiotic unless your doctor tells you to stop. Keep taking your antibiotic even if you feel better and you think you don’t need your antibiotic anymore.
If you stop your treatment early, your infection may return quickly and you can develop resistance to the antibiotic you were using previously. Your antibiotic may not work as well the next time you use it.
Manufacturers Respond To The Fda
The FDA received at least three responses to its list ofphenazopyridine questions within a 6-month period. The ConsumerHealthcare Products Association asked the FDA to reviewphenazopyridine, but completely sidestepped the issue ofcarcinogenicity.11 A submission from PolymedicaPharmaceuticals asserted that urinarydiscomfort should be self-treatable, and further argued against warningpatients on product labels that they may need a concomitantantibacterial.12 Polymedica also claimed that phenazopyridinedosages of 190 to 195 mg are safe and effective, but did not submitclinical dosage studies to support its assertions. Polymedica arguedagainst including any carcinogenesis statement. In short, the submissionwas entirely laudatory about phenazopyridine, although it did notreport newly conducted clinical studies, as would have been required bythe FDA to establish safety and efficacy.
A brief submission from Johnson & Johnson made essentially the same arguments as Polymedica, denying theneed for carcinogenicity labeling.13 This submission also failed to include new clinical studies providing evidence of safety and efficacy.
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Antibiotics Used For Uncomplicated Utis
If you are a healthy individual whose urinary tract is anatomically and functionally normal and you have no known heightened UTI susceptibility youve got whats dubbed an uncomplicated UTI, according to guidelines published in August 2019 in the Journal of Urology. For these individuals, antibiotics are considered the first-line of treatment.
The type of antibiotics you are prescribed and for how long is contingent on the type of bacteria detected in your urine, your current health status, and whether your UTI is uncomplicated or complicated. Depending on which antibiotic your doctor prescribes, women may need a single dose or up to a five-day course. For men, antibiotics are usually given for a slightly longer period of time, notes UpToDate.
Typically, if you are diagnosed with an uncomplicated UTI, one of the following will be prescribed as first-line treatment:
The following antibiotics are considered second-line treatments for UTI. They are generally chosen because of resistance patterns or allergy considerations:
Are Quinolones Safe
The fluoroquinolones, such as ciprofloxacin and levofloxacin have also been commonly used for simple UTIs however, FDA safety recommendations strongly suggest that this class be reserved for more serious infections and only be used if other appropriate antibiotics are not an option.
- An FDA safety review found that both oral and injectable fluoroquinolones are associated with serious and potentially disabling side effects involving tendons, muscles, joints, nerves and the central nervous system.
- These adverse effects can occur soon after administration to weeks after exposure, and may potentially be permanent.
- Patients should discuss the use of fluoroquinolones and their side effects with their healthcare provider.
However, certain oral fluoroquinolones may be appropriate for more complicated UTIs, including pyelonephritis and complicated UTIs in men with prostate involvement. For the outpatient treatment of uncomplicated pyelonephritis, the following quinolones may be appropriate. Based on resistance patterns , an inital dose of a long-acting parenteral antimicrobial, such as ceftriaxone, may be needed, or a 24-hour dose of an aminoglycoside.
Patients should be informed of the most current FDA warnings surrounding the use of fluoroquinolone antibiotics.
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How To Feel Better
If your healthcare professional prescribes you antibiotics:
- Take antibiotics exactly as your healthcare professional tells you.
- Do not share your antibiotics with others.
- Do not save antibiotics for later. Talk to your healthcare professional about safely discarding leftover antibiotics.
Drink plenty of water or other fluids. Your healthcare professional might also recommend medicine to help lessen the pain or discomfort. Talk with your healthcare professional if you have any questions about your antibiotics.
Can Azo Urinary Tract Defense Get Rid Of A Uti
No, AZO Urinary Tract Defense does not cure a urinary tract infection. Its purpose is to keep you comfortable and to control the infection until you can see your primary care provider. Your doctor will prescribe an antibiotic medication capable of eliminating the bacteria responsible for the infection.
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How Long Does A Uti Last
Urinary tract infections usually go away after the first few days of antibiotics treatment. Depending on the severity of the infection, they may last a bit longer. If you often get UTIs, your healthcare provider may prescribe low-dose antibiotics for a few months at a time. If you have a UTI, over-the-counter products may help ease your symptoms while you receive antibiotic treatment.
Advantages Of Buying Good Quality Products
1. Buying good quality products will save you money in the long-term
If you want to save money in the long-term, buy quality products. You may be tempted by cheaper alternatives that are less likely to break, but they wont last as long and require more replacement parts. So if youre thinking of buying the urinary tract infection test strips walgreens or other durable goods, wait until you can afford the higher price tag for a better quality item. Youll end up saving more money in the long run.
Is it worth buying a quality product that will last a long time? Investing in products that will last, and not just buy something because its cheap. You can spend more money on two or three more inexpensive items than one good quality item. So, dont compromise now if you know what you want.
2. Good quality items last longer and are more durable
The quality of items you buy determines how long they last. Things cheaply made will not last as long and are more likely to break or wear out quicker than their better-made counterparts. If you want your items to last longer, you must invest in good quality products.
The consumer is an integral part of the equation to keep in mind when looking for the last items. What are your expectations? The longer you plan on using an item, the more critical it becomes to choose one that will stand up to daily wear and tear.
3. Buying good quality products will make you feel better about your purchase
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