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Is Ciprofloxacin Used To Treat Urinary Tract Infections

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Avoid Alcohol And Caffeine

PharmD overviews the uses and common side effects of Ciprofloxacin

Alcohol and caffeine are two things you should really not consume until your UTI is gone. Thats because they do the exact opposite of water: they make your urine very concentrated, which can irritate the bladder. You are more likely to experience more pain or discomfort while urinating if you continue to consume these beverages while you have a UTI.

But what if you just cant skip your morning cup of coffee? If you need caffeine in the morning to avoid getting a headache, try to drink just enough to prevent it or switch to a beverage with less caffeine content, like tea, until your UTI is better. Also, be sure to drink an extra cup or two of water to account for the caffeine you did have.

Are Nitrofurantoin And Ciprofloxacin Safe To Use While Pregnant Or Breastfeeding


Although there are no adequate studies of nitrofurantoin in pregnant women, many women have safely used it during pregnancy. However, nitrofurantoin should not be used near the time of delivery since it interferes with the immature enzyme systems in newborns’ red blood cells, damaging the cells and resulting in anemia.

Nitrofurantoin is distributed into breast milk, and women who are breastfeeding should use with caution.


Doctors suggest that women who are pregnant or breastfeeding should not use this antibiotic, because they do not know if it is safe.

What If I Forget To Take It

If you forget a dose, take it as soon as you remember, unless it’s nearly time for your next dose. In this case, just skip the missed dose and take your next one as normal.

Make sure you finish your full course of antibiotics. Do not have a double dose to make up for a missed dose.

If you forget doses often, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to remember your medicines

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How To Apply The Eyedrops

You’ll usually put 1 or 2 drops into the affected eye 4 times a day.

For severe infections, your doctor may tell you to use the drops as often as every 15 minutes for the first 6 hours. You can then reduce how often you use it.

  • Gently pull down your lower eyelid with a clean finger and tilt your head back.
  • Hold the bottle over your eye and allow a single drop to fall into the space between your lower lid and your eye.
  • Wipe away any extra liquid with a clean tissue.
  • Put in a second drop if you have been told to.

Do not touch your eye or eyelid with the dropper as it may cause infection to spread.

Diagnosis And Management Of Uncomplicated Urinary Tract Infections

Cipro for UTI: Uses, side effects, and alternatives

SUSAN A. MEHNERT-KAY, M.D., University of Oklahoma College of MedicineTulsa, Tulsa, Oklahoma

Am Fam Physician. 2005 Aug 1 72:451-456.

Patient information: See related handout on urinary tract infections, written by the author of this article.

Most uncomplicated urinary tract infections occur in women who are sexually active, with far fewer cases occurring in older women, those who are pregnant, and in men. Although the incidence of urinary tract infection has not changed substantially over the last 10 years, the diagnostic criteria, bacterial resistance patterns, and recommended treatment have changed. Escherichia coli is the leading cause of urinary tract infections, followed by Staphylococcus saprophyticus. Trimethoprim-sulfamethoxazole has been the standard therapy for urinary tract infection however, E. coli is becoming increasingly resistant to medications. Many experts support using ciprofloxacin as an alternative and, in some cases, as the preferred first-line agent. However, others caution that widespread use of ciprofloxacin will promote increased resistance.


A three-day course of trimethoprim-sulfamethoxazole is recommended as empiric therapy of uncomplicated urinary tract infections in women, in areas where the rate of resistanceEscherichia coli are less than 20 percent.


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What Should I Do If I Forget A Dose

If you miss a dose of ciprofloxacin tablets or suspension and it is 6 hours or more before the next dose, take the missed dose as soon as you remember it and then take the next dose at the scheduled time. However, if you miss a dose of ciprofloxacin tablets or suspension and it is less than 6 hours before the next dose, skip the missed dose and continue your regular dosing schedule.

If you miss a dose of the extended-release tablet and it is 8 hours or more before the next dose, take the dose as soon as you remember it and then take the next dose at the scheduled time. However, if you miss a dose of ciprofloxacin extended-release tablets and it is less than 8 hours before the next dose, skip the missed dose and continue your regular dosing schedule.

Do not take a double dose to make up for a missed one. Do not take more than two doses of the tablets or suspension or more than one dose of the extended-release tablets in one day.

Cipro And Other Medications

Below is a list of medications that can interact with Cipro. This list does not contain all drugs that may interact with Cipro.

Before taking Cipro, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.


Many antacids contain calcium carbonate, magnesium hydroxide, and aluminum hydroxide. These ingredients can bind to Cipro and prevent your body from absorbing it. This can decrease how well Cipro works.

To avoid this interaction, take Cipro at least two hours before taking an antacid, or six hours afterward.

Anticoagulant drugs

Taking Cipro with oral anticoagulant drugs such as warfarin might increase the anticoagulant effects. This might result in increased bleeding. If you take an anticoagulant, your doctor may need to monitor your bleeding risk more frequently if you take Cipro.

Drugs that prolong the QT interval

Certain medications prolong your QT interval, which means they might affect the rhythm of your heartbeat. Taking Cipro with these drugs can increase the risk of having a dangerous irregular heartbeat. Cipro should be avoided or used very carefully with these medications.

Examples of these medications include:


Diabetes drugs




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What Drugs Interact With Nitrofurantoin And Ciprofloxacin


  • High doses of probenecid or sulfinpyrazone can partially block the kidneys’ elimination of nitrofurantoin. This can increase the blood concentrations of nitrofurantoin and the risk of toxicity from nitrofurantoin.
  • Concomitant administration of a magnesium trisilicate antacid may decrease the absorption of nitrofurantoin, reducing the effectiveness of nitrofurantoin.
  • Nitrofurantoin may reduce the activity of live tuberculosisvaccine and live typhoid vaccine. In laboratory tests, nitrofurantoin reduced the effect of quinolone antibiotics, for example, norfloxacin . Therefore, nitrofurantoin should not be combined with quinolone antibiotics.


Critical Appraisal Of Individual Studies

What are some common antibiotics used to treat UTIs?

The included systematic reviews were critically appraised by one reviewer using the AMSTAR 2 checklist, randomized and non-randomized studies were critically appraised using the Downs and Black checklist, and guidelines were assessed with the AGREE II instrument. Summary scores were not calculated for the included studies rather, a review of the strengths and limitations of each included study were described narratively.

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Are There Any Drug Interactions I Should Be Aware Of

The following drugs should not be used or should be used with caution when given with ciprofloxacin: products containing magnesium, aluminum, or calcium , other antibiotics, corticosteroids, cyclosporine, doxorubicin, drugs that affect the heart rhythm, fentanyl, iron, zinc, levothyroxine, mycophenolate mofetil, methotrexate, nitrofurantoin, probenecid, quinidine, sildenafil, sucralfate, theophylline, and warfarin.

Be sure to tell your veterinarian about any medications that your pet is taking.

How Long Does It Take To Work

Cipro begins to work against bacterial infections within hours of when you take it. However, you may not notice improvement in your symptoms for a few days.

The Cipro dosage your doctor prescribes will depend on several factors. These include:

  • the type and severity of the condition youre using Cipro to treat
  • your age
  • the form of Cipro you take
  • other medical conditions you may have, such as kidney disease

Typically, your doctor will start you on a low dosage and adjust it over time to reach the dosage thats right for you. Theyll ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.

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Treatment Options For Urinary Tract Infections

Ladies, if you think you have a urinary tract infection, you are probably right. One study found that women who self-diagnose a UTI are right 84% of the time.

You can apply this know-how to partner with your health care provider to pick the right treatment The go-to treatment of a UTI, which is caused by a bacteria, is antibiotics. Your questions about treatment decisions can make a difference, especially since antibiotic recommendations have shifted and not all doctors have changed their practices.

What Is Ciprofloxacin Oral

Ciprofloxacin For UTI (Urinary Tract Infections): What To ...

Ciprofloxacin is a systemic fluoroquinolone antibiotic, usually used as an alternative to enrofloxacin to treat bacterial infections. It is most often used to treat urinary tract infections or skin infections.

Its use in cats and dogs to treat bacterial infections is off label or extra label. Many drugs are commonly prescribed for off label use in veterinary medicine. In these instances, follow your veterinarians directions and cautions very carefully as their directions may be significantly different from those on the label.

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How Does Cipro Work

Cipro is an antibiotic in the class of fluoroquinolones. This type of antibiotic is bactericidal. This means that it directly kills bacteria. It does this by blocking enzymes that are needed for bacteria survival.

Cipro is a broad-spectrum antibiotic. This means it works against many different types of bacteria. However, many bacteria have grown to be resistant to Cipro. Resistant bacteria can no longer be treated with a certain drug.

Ciprofloxacin May Cause Side Effects Tell Your Doctor If Any Of These Symptoms Are Severe Or Do Not Go Away:

  • nausea
  • ongoing or worsening cough
  • yellowing of the skin or eyes pale skin dark urine or light colored stool
  • extreme thirst or hunger pale skin feeling shaky or trembling fast or fluttering heartbeat sweating frequent urination trembling blurred vision or unusual anxiety
  • fainting or loss of consciousness
  • sudden pain in the chest, stomach, or back

Ciprofloxacin may cause problems with bones, joints, and tissues around joints in children. Ciprofloxacin should not normally be given to children younger than 18 years of age unless they have certain serious infections that cannot be treated with other antibiotics or they have been exposed to plague or anthrax in the air. If your doctor prescribes ciprofloxacin for your child, be sure to tell the doctor if your child has or has ever had joint-related problems. Call your doctor if your child develops joint problems such as pain or swelling while taking ciprofloxacin or after treatment with ciprofloxacin.

Talk to your doctor about the risks of taking ciprofloxacin or giving ciprofloxacin to your child.

Ciprofloxacin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s MedWatch Adverse Event Reporting program online or by phone .

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Quantity Of Research Available

A total of 442 citations were identified in the literature search. Following screening of titles and abstracts, 404 citations were excluded and 38 potentially relevant reports from the electronic search were retrieved for full-text review. Nine potentially relevant publications were retrieved from the grey literature search for full-text review. Of these potentially relevant articles, 19 publications were excluded for various reasons, and 28 publications met the inclusion criteria and were included in this report. These comprised three systematic reviews, nine randomized controlled trials , seven non-randomized studies, and nine evidence-based guidelines . presents the PRISMA flowchart of the study selection. Additional references of potential interest are provided in .

How To Take Cipro

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Take Cipro exactly according to your doctors instructions. You might start to feel better before you finish your entire Cipro treatment. Even if you start to feel better, dont stop taking Cipro. In many cases, its important to finish the entire treatment to make sure the infection doesnt come back.

If youre feeling better and want to stop Cipro early, be sure to talk with your doctor first to make sure its safe to do so.

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How Does The Drug Work

Ciprofloxacin and enrofloxacin have similar modes of action, ciprofloxacins absorption to the body from the bloodstream in pets can be variable and significantly less than enrofloxacin. It begins working in about 1-2 hours after it is given, and you should notice that your pet is feeling better about 2 days after you start the medication. It is important to give this medication to your pet for the entire time prescribed by your veterinarian, even if it appears that your pet is feeling better.

How To Use The Eardrops

Put up to 5 drops into the affected ear twice a day, or as your doctor advises.

  • Warm the drops by holding the container in your hands for a few minutes.
  • Tilt your head and bring the container up to the affected ear, with the open end close to your ear hole.
  • Squeeze the drops into your ear.
  • If you can, lie down for at least 5 minutes afterwards.
  • If you are only treating 1 ear, turn your head to one side, so your affected ear is towards the ceiling.

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What Are Nitrofurantoin And Ciprofloxacin

Nitrofurantoin is an antibiotic specifically used for treating urinary tract infections caused by several types of bacteria including E. Coli, Enterobacter cystitis, Enterococcus, Klebsiella, and Staphylococcus aureus. Nitrofurantoin interferes with the production of bacterial proteins, DNA, and cell walls. Bacteria cannot survive without a cell wall or multiply without DNA. There are three forms of nitrofurantoin: Furadantin, a microcrystalline form Macrodantin, a macrocrystalline and Macrobid, a sustained release form of macrocrystalline. The macrocrystalline form is more slowly absorbed than the microcrystalline form and is used for patients who cannot tolerate the microcrystalline form.

Ciprofloxacin is a fluoroquinolone antibiotic used to treat bacterial infections. It stops the multiplication of bacteria by inhibiting the reproduction and repair of their genetic material . Other fluoroquinolones include levofloxacin , ofloxacin , gatifloxacin , norfloxacin , moxifloxacin , and trovafloxacin . Ciprofloxacin is used to treat infections of the skin, lungs or airways, bones, joints, and urinary tract, infectious diarrheas, anthrax patients with fever and low white blood cell counts and intra-abdominal infections, typhoid fever, cervical and urethral gonorrhea, chronic bacterial prostatitis, and acute uncomplicated cystitis.

In other persons, lung injury may occur after approximately a month of treatment. Symptoms include:

  • Difficulty breathing
  • Cough


  • Nausea

What Is The Dosage Of Nitrofurantoin Vs Ciprofloxacin

Cipro for UTI: Uses, side effects, and alternatives ...


  • The recommended adult dose for treating urinary tract infections is 50-100 mg 4 times daily or 100 mg every 12 hours for 7 days or for 3 days after obtaining sterile urine.
  • Nitrofurantoin can be taken with or without meals. Taking it with meals increases its absorption into the body.
  • The suspension can be mixed with water, milk, juice, or infant formula.
  • It also is used once a day to prevent urinary tract infections.
  • It should not be used in persons with poor kidney function.


  • For most infections, the recommended oral dose for adults is 250-750 mg every 12 hours or 500-1000 mg every 24 hours.
  • The usual intravenous dose is 200-400 mg every 8-12 hours.

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How To Cope With Side Effects

What to do about:

  • feeling sick â stick to simple meals and do not eat rich or spicy food while you’re taking this medicine. It might help to take ciprofloxacin after you have had a meal or snack
  • diarrhoea after taking the tablets or liquid â drink lots of fluids, such as water or squash, to avoid dehydration. Signs of dehydration include peeing less than usual or having dark strong-smelling pee. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor
  • discomfort or redness in the eyes after using the drops or ointment â this should go away on its own. Do not drive or operate heavy machinery until your eyes feel comfortable again and your vision is clear
  • bad taste in your mouth after using the eyedrops or ointment â this should not last long after using your medicine. Drink some water or juice, or chew some sugar-free gum
  • white specks on the surface of your eye after using the eyedrops or ointment â keep taking your ciprofloxacin but tell your doctor if these side effects bother you or do not go away

Antibiotics That Shouldn’t Be A First Choice For Uncomplicated Utis

Other antibiotics appear to be overused, and some physicians may misuse non-recommended antibiotics as first-line treatments. Ciprofloxacin is used in 35% of uncomplicated UTIs, while levofloxacin is used in 2%. These antibiotics can be important treatments in some cases of more complicated UTIs, but can have dangerous side effects.

The U.S. Food and Drug Administration warns that the use of these drugs should be restricted because of their potentially disabling side effects involving tendons, muscles, joints, nerves and the central nervous system. Additionally, in many parts of the country, bacteria commonly causing UTIs are becoming resistant to these antibiotics.

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